Microarray Quality Control

Microarray technology provides researchers in the life scienceswith a revolutionary tool for measuring gene expression. However,this highly developed process involves multiple steps, from sampleselection to data analysis, each susceptible to potentially costlyerrors. Without sound quality control, experimental microarrays mayproduce useless or, even worse, misleading results. Microarray Quality Control provides a comprehensive resource forensuring quality control in every step of this complex process.From experimental design to data processing, analysis, andinterpretation, the emphasis in this text remains on practicaladvice for each stage of planning and running a microarray study.Chapters cover: * Quality of biological samples * Quality of DNA * Hybridization protocols Scanning * Data acquisition * Image analysis * Data analysis Written for the broad group of workers-biologists, mathematicians,statisticians, engineers, physicians, and computationalscientists-involved in microarray studies, Microarray QualityControl features a straightforward style easily accessed by variousdisciplines. Useful checklists and tips help ensure the integrityof results, and each chapter contains a thorough review ofpertinent literature. The only complete, systematic treatment of the topic available,Microarray Quality Control offers students and practitioners aninvaluable resource for improving experimental quality andefficiency.