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Veteran journalist Jack McEvoy has tracked down murders in the past, but when a woman with whom he had a one-night stand is brutally killed, he realizes that this time, he might be facing a criminal mind like no other. Ignoring the warnings from police and his boss, he investigates the case and links it to other mysterious murders throughout the country. The killer chooses his victims based on genetic information that they themselves have shared. Jack delves into the dark web to try and unmask the serial killer's identity before it's too late.