Structure and Function in Cell Signalling

"This book contains extremely detailed and informative contenton structure and function of ligands, receptors, and signallingintermediates plus interactions ... the extent of detail andappropriate referencing is impressive." -MicrobiologyToday, July 2009 "A very well-written book suitable for use as a reference ortextbook for an undergraduate subject in cell signalling. Forresearchers interested in the molecular basis of cell signallingand how aberrant regulation of cell signalling proteins causesdiseases, this is an excellent resource of biochemical andstructural information." -Australian Biochemist, August2009 "From basics to details, this is an elegantly written andcarefully edited book. The chapters on cell cycle control andoncogenesis are particularly fascinating and valuable to biomedicalresearch. This is the book to have if you are interested inmolecular mechanisms of signal transduction. It is a greatintroduction to the literature that will be welcomed by studentsand experts alike." -Doody's, January 2009 This text is a concise and accessible introduction to thedynamic but complex field of signal transduction. Rather thansimply cataloguing all signalling molecules and delineating everyknown pathway, this book aims to break signalling down into commonelements and activities - the 'nuts and bolts' ofcellular information exchange. With an emphasis on clarity of presentation throughout, the bookteaches the basic principles focusing on a mature core ofknowledge, providing students with a foundation of learning in thiscomplex and potentially confusing subject. It also addresses theissue of variation in the numbering of key amino acids as well asfeaturing interaction with RasMol software, and exercises to aidunderstanding. * An accessible introduction to the complex field of cellsignalling * Interacts with RasMol software - freely downloadable forviewing structures in 3D * Includes exercises and clear instructions in the use ofRasMol * Well illustrated in full colour throughout Structure and Function in Cell Signalling is aninvaluable resource to students across a range of life sciencedegree programmes including biochemistry, cell and molecularbiology, physiology, biomedicine and oncology. This book provides aclear, accessible introduction to this rapidly expanding field.